Newsroom News Archive Publications Contact Us for Experts  

News from:

 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | RSSFeeds  

NEWS RELEASE
OCTOBER 21, 2009
  Penn Investigators Recipients of New NIH Award for Transformative Research
Back to Article
   

To encode a random shRNA requires a random DNA sequence – of 29 nucleotides in this case – and its reverse complement in the same DNA strand, separated by a non-complementary loop sequence. A library of such sequences can be used in pooled, cell-based screens for small RNA therapeutics, biological tools, and/or biological probes.

Credit: Robert Wilson, PhD, University of Pennsylvania School of Medicine
To encode a random shRNA requires a random DNA sequence – of 29 nucleotides in this case – and its reverse complement in the same DNA strand, separated by a non-complementary loop sequence. A library of such sequences can be used in pooled, cell-based screens for small RNA therapeutics, biological tools, and/or biological probes. (Robert Wilson, PhD, University of Pennsylvania School of Medicine)
 


About Penn Medicine   Contact Us   Site Map   Privacy Statement   Legal Disclaimer   Terms of Use

Penn Medicine , Philadelphia, PA 1-800-789-PENN © 2009, The Trustees of the University of Pennsylvania